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Sex Transm Infect. 2011 Aug;87(5):385-8. doi: 10.1136/sextrans-2011-050005.

The association of current hormonal contraceptive use with type-specific HPV detection.

Author information

  • 1JHUBMC, ID Division, 4940 Eastern Ave, B3N Suite 352, Baltimore, MD 21224, USA. kghanem@jhmi.edu

Abstract

BACKGROUND:

Increased duration of hormonal contraceptive (HC) use may be positively associated with the risk of invasive cervical cancer.

METHODS:

This is a secondary analysis from the HPV Sentinel Surveillance Study. The authors examined the association between type-specific human papillomavirus (HPV) detection and current HC use among 7718 women attending 26 sexually transmitted disease, family planning and primary care clinics in the USA.

RESULTS:

There was an association between HC use and HPV-16 detection (adjusted prevalence rate ratio 1.34 (95% CI 1.05 to 1.71) for oral contraceptive users and 1.41 (1.01 to 2.04) for depot-medroxyprogesterone acetate users); there was no association between HC use and detection of other HPV types or any HPV overall.

CONCLUSIONS:

Longitudinal studies are needed to better define this type-specific association and its clinical significance.

PMID:
21772042
[PubMed - indexed for MEDLINE]
PMCID:
PMC3512558
Free PMC Article
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