Format

Send to:

Choose Destination
See comment in PubMed Commons below
J Am Acad Dermatol. 2011 Aug;65(2):253-61; quiz 262. doi: 10.1016/j.jaad.2010.11.062.

Skin cancer in solid organ transplant recipients: advances in therapy and management: part I. Epidemiology of skin cancer in solid organ transplant recipients.

Author information

  • 1Department of Dermatology, Emory University, Atlanta, Georgia 30322, USA. taranadine@aol.com

Abstract

Skin cancer is the most frequent malignancy in organ transplant recipients, 95% of which are nonmelanoma skin cancer, especially squamous cell and basal cell carcinomas. This paper also discusses the incidence of other tumors (eg, melanoma, Merkel cell carcinoma, and Kaposi sarcoma) that are also increased in organ transplant patients compared to the general population. Part I of this two-part series describes the latest data concerning the epidemiologic and pathogenic aspects of nonmelanoma skin cancer development in solid organ transplant recipients. This review also highlights the concept of "field cancerization," represented by extensive areas of actinic damage and epidermal dysplasia, which accounts for increased risk of aggressive skin cancer development in susceptible patients.

Copyright © 2010 American Academy of Dermatology, Inc. Published by Mosby, Inc. All rights reserved.

PMID:
21763561
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk