Clin Genet. 2011 Sep;80(3):240-1. doi: 10.1111/j.1399-0004.2011.01752.x.

DNMT1 links aberrant DNA methylation to hereditary sensory neuropathy.

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Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, University of British Columbia, Vancouver, BC V5Z 4H4, Canada. ghannad@cmmt.ubc.ca

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Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. [Nat Genet. 2011]
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss.Klein CJ, Botuyan MV, Wu Y, Ward CJ, Nicholson GA, Hammans S, Hojo K, Yamanishi H, Karpf AR, Wallace DC, et al. Nat Genet. 2011 Jun; 43(6):595-600. Epub 2011 May 1.

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Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss. [Nat Genet. 2011]
Mutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing loss.
Klein CJ, Botuyan MV, Wu Y, Ward CJ, Nicholson GA, Hammans S, Hojo K, Yamanishi H, Karpf AR, Wallace DC, et al. Nat Genet. 2011 Jun; 43(6):595-600. Epub 2011 May 1.
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. [Nat Genet. 2003]
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
Robert MF, Morin S, Beaulieu N, Gauthier F, Chute IC, Barsalou A, MacLeod AR. Nat Genet. 2003 Jan; 33(1):61-5. Epub 2002 Dec 23.
Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1). [Proc Natl Acad Sci U S A. 2011]
Structural insight into maintenance methylation by mouse DNA methyltransferase 1 (Dnmt1).
Takeshita K, Suetake I, Yamashita E, Suga M, Narita H, Nakagawa A, Tajima S. Proc Natl Acad Sci U S A. 2011 May 31; 108(22):9055-9. Epub 2011 Apr 25.
Review Regulation of the DNA methylation machinery and its role in cellular transformation. [Prog Nucleic Acid Res Mol Biol...]
Review Regulation of the DNA methylation machinery and its role in cellular transformation.
Szyf M, Detich N. Prog Nucleic Acid Res Mol Biol. 2001; 69:47-79.
Review Mammalian cytosine DNA methyltransferase Dnmt1: enzymatic mechanism, novel mechanism-based inhibitors, and RNA-directed DNA methylation. [Curr Med Chem. 2008]
Review Mammalian cytosine DNA methyltransferase Dnmt1: enzymatic mechanism, novel mechanism-based inhibitors, and RNA-directed DNA methylation.
Svedruzić ZM. Curr Med Chem. 2008; 15(1):92-106.

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DNMT1 links aberrant DNA methylation to hereditary sensory neuropathy.
DNMT1 links aberrant DNA methylation to hereditary sensory neuropathy.
Clin Genet. 2011 Sep ;80(3):240-1. doi: 10.1111/j.1399-0004.2011.01752.x.

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