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Clin Ophthalmol. 2011;5:751-8. doi: 10.2147/OPTH.S7633. Epub 2011 Jun 3.

Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery.

Author information

  • 1Department of Ophthalmology, Vanderbilt University, Nashville, TN, USA.

Abstract

BACKGROUND:

The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail(®)) in the treatment of pain and inflammation after cataract surgery.

METHODS:

Literature search and expert opinion of the authors.

RESULTS:

Recent studies indicate greater intraocular drug levels in the anterior chamber and iris-ciliary body after topical application of Acuvail in comparison with older formulations of ketorolac. A large randomized, multicenter, placebo-controlled study demonstrated significantly less inflammation and pain after cataract surgery using Acuvail.

CONCLUSION:

Acuvail appears to be effective in reducing post-cataract surgery pain and inflammation.

KEYWORDS:

Acuvail®; cystoid macular edema; ketorolac tromethamine; nonsteroidal anti-inflammatory drugs; postsurgical

PMID:
21750608
[PubMed]
PMCID:
PMC3130912
Free PMC Article
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