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Curr Biol. 2010 Apr 27;20(8):R368-70. doi: 10.1016/j.cub.2010.02.053.

Ribosomal genes: safety in numbers.

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  • 1Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London W12 0NN, UK.


The presence of inactive units in tandem arrays of ribosomal genes (rDNA) has been linked to increased transcriptional capacity, but a recent study indicates that inactive units are necessary for sister chromatid cohesion and genetic stability of rDNA.

Copyright © 2010 Elsevier Ltd. All rights reserved.

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