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Curr Biol. 2010 Apr 27;20(8):R368-70. doi: 10.1016/j.cub.2010.02.053.

Ribosomal genes: safety in numbers.

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  • Cell Cycle Group, MRC Clinical Sciences Centre, Imperial College London, Hammersmith Hospital, London W12 0NN, UK. luis.aragon@csc.mrc.ac.uk


The presence of inactive units in tandem arrays of ribosomal genes (rDNA) has been linked to increased transcriptional capacity, but a recent study indicates that inactive units are necessary for sister chromatid cohesion and genetic stability of rDNA.

Copyright © 2010 Elsevier Ltd. All rights reserved.

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