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Emerg Infect Dis. 2011 Jun;17(6):1091-4. doi: 10.3201/eid/1706.101242.

Salmonella enterica Serotype Typhi with nonclassical quinolone resistance phenotype.

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  • 1Institut Pasteur, Paris, France.

Abstract

We report Salmonella enterica serotype Typhi strains with a nonclassical quinolone resistance phenotype (i.e., decreased susceptibility to ciprofloxacin but with susceptibility to nalidixic acid) associated with a nonsynonymous mutation at codon 464 of the gyrB gene. These strains, not detected by the nalidixic acid disk screening test, can result in fluoroquinolone treatment failure.

PMID:
21749778
[PubMed - indexed for MEDLINE]
PMCID:
PMC3358197
Free PMC Article
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