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Pediatr Blood Cancer. 2011 Dec 1;57(6):1071-3. doi: 10.1002/pbc.23241. Epub 2011 Jul 9.

Antiangiogenic treatment as a pre-operative management of alveolar soft-part sarcoma.

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  • 1Department of Paediatric Oncology, Hospital Sant Joan de Déu, Barcelona, Spain.


Alveolar soft-part sarcoma (ASPS) is a rare tumor. Cure is based solely on radical surgery. The general prognosis is poor. The tongue is an unusual site in adults, but not in children. Tumor removal can cause a severe impact on quality of life, even if reconstruction is possible. ASPS is a highly vascularized tumor and antiangiogenic therapy may have a role. We describe the use of the antiangiogenic combination bevacizumab and celecoxib in the preoperative management of a patient with an ASPS of the tongue.

Copyright © 2011 Wiley-Liss, Inc.

[PubMed - indexed for MEDLINE]
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