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Pediatr Blood Cancer. 2011 Sep;57(3):524-7. doi: 10.1002/pbc.23051. Epub 2011 Jan 24.

Gastric adenocarcinoma in children and adolescents.

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  • 1The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA. vsubbiah@mdanderson.org


Gastric adenocarcinoma (GAC) is an extremely rare cancer in children with very limited information on the clinical presentation and outcome. We report five pediatric patients with GAC-treated between 1990 and 2008 at our institution. Median age at diagnosis was 17 years (range: 8-17). Our case series suggests that pediatric GAC patients present with diffuse metastatic disease (four patients) and with patterns of spread similar to adult GAC. Initial chemotherapy was mainly platinum-based. Median time to progression was 4 months. The only long-term survivor was a patient with localized disease who had complete surgical removal of primary tumor.

Copyright © 2011 Wiley-Liss, Inc.

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