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J Virol. 1990 Dec;64(12):6274-7.

Plus-strand origin for human immunodeficiency virus type 1: implications for integration.

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  • 1Department of Microbiology, School of Medicine, University of Washington, Seattle 98195.

Abstract

The start site for human immunodeficiency virus type 1 plus strands within the polypurine tract was mapped by an in vitro analysis to the sequence 5'-ACTG....From this result, it can be inferred that integration of human immunodeficiency virus type 1 must be accompanied by the loss of two base pairs from the polypurine tract-primed long terminal repeat end.

PMID:
2173791
[PubMed - indexed for MEDLINE]
PMCID:
PMC248804
Free PMC Article
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