Abstract
The relationship between anti-TNF therapy and development of lymphoma in Rheumatoid arthritis (RA) patients is controversial. However lymphomas of unusual types and sites have been reported among RA patients receiving anti-TNF therapy. Primary lymphoma of the breast is a rare entity and has never been reported to occur among RA patients taking anti-TNF therapy. This is the first case of primary lymphoma of the breast reported among RA patients on anti-TNF therapy. Rheumatoid arthritis patients currently on anti-TNF therapy should undergo routine gynecological examination.
MeSH terms
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Aged
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Antirheumatic Agents / adverse effects
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Antirheumatic Agents / therapeutic use*
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Arthritis, Rheumatoid / drug therapy*
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Breast Neoplasms / chemically induced*
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Etanercept
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Female
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Humans
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Immunoglobulin G / adverse effects
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Immunoglobulin G / therapeutic use
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Lymphoma / chemically induced*
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Methotrexate / adverse effects
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Methotrexate / therapeutic use
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Receptors, Tumor Necrosis Factor / therapeutic use
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Tumor Necrosis Factor-alpha / adverse effects
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Tumor Necrosis Factor-alpha / therapeutic use*
Substances
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Antirheumatic Agents
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Immunoglobulin G
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Receptors, Tumor Necrosis Factor
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Tumor Necrosis Factor-alpha
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Etanercept
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Methotrexate