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Clin Imaging. 2011 Jul-Aug;35(4):288-93. doi: 10.1016/j.clinimag.2010.07.005.

Magnetic resonance spectroscopic imaging of benign prostatic tissue: findings at 3.0 T compared to 1.5 T-initial experience.

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  • 1Department of Radiology, University of California, San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0628, USA.


In a retrospective study of 71 voxels of benign peripheral zone tissue from 3 men who underwent endorectal magnetic resonance (MR) spectroscopic imaging of the prostate at both 1.5 and 3 T, 21 voxels that appeared more malignant at 3 T to either of two readers demonstrated significantly higher levels of choline and polyamines at 3 T compared to 1.5 T using a Wilcoxon ranked-sum test; awareness of this selective amplification of these metabolic signals at high field strength may help avoid overdiagnosis of prostate cancer.

Copyright © 2011. Published by Elsevier Inc.

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