The interplay of YKL-40 and leptin in type 2 diabetic obese patients

Hala O El-Mesallamy; Ahmed M Mostafa; Ashraf I Amin; Ebtehal El Demerdash

doi:10.1016/j.diabres.2011.05.040

The interplay of YKL-40 and leptin in type 2 diabetic obese patients

Diabetes Res Clin Pract. 2011 Sep;93(3):e113-6. doi: 10.1016/j.diabres.2011.05.040. Epub 2011 Jun 28.

Authors

Hala O El-Mesallamy¹, Ahmed M Mostafa, Ashraf I Amin, Ebtehal El Demerdash

Affiliation

¹ Biochemistry Department, Faculty of Pharmacy, Ain Shams University, Abbassia, Cairo, Egypt.

PMID: 21715039
DOI: 10.1016/j.diabres.2011.05.040

Abstract

Recently, YKL-40 has been identified as a new inflammatory marker of type 2 diabetes mellitus (T2DM), while leptin is one of the most important adipose derived hormones. However, the relationship between them has not been elucidated. Therefore this study aimed to study their correlation in obese T2DM patients.

MeSH terms

Adipokines / blood*
Adult
Chitinase-3-Like Protein 1
Diabetes Mellitus, Type 2 / blood*
Fasting / blood
Female
Humans
Lectins / blood*
Leptin / blood*
Male
Middle Aged
Obesity / blood*

Substances

Adipokines
CHI3L1 protein, human
Chitinase-3-Like Protein 1
Lectins
Leptin