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Addiction. 2011 Dec;106(12):2178-85. doi: 10.1111/j.1360-0443.2011.03559.x. Epub 2011 Oct 7.

Co-occurrence of obsessive-compulsive disorder and substance use disorder in the general population.

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  • 1Department of Psychiatry, Academical Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.

Abstract

AIM:

Very little is known about the relationship between obsessive-compulsive disorder (OCD) and substance use disorder (SUD). The aim of this study is to compare the co-occurrence of OCD with SUD to the co-occurrence of SUD with other psychiatric disorders in a representative community sample.

DESIGN:

In order to examine the association of SUD and OCD, logistic regression analyses were used generating odds ratios and 95% confidence intervals for life-time prevalence and 12-month prevalence.

SETTING AND PARTICIPANTS:

  Cross-sectional data were derived from the Netherlands Mental Health Survey and Incidence Study (NEMESIS), a large representative sample of the Dutch population (n = 7076).

MEASUREMENTS:

  The Composite International Diagnostic Interview (CIDI) 1.1 was used to assess Diagnostic and Statistical Manual of Mental Disorders Axis I criteria for psychiatric disorders.

FINDINGS:

  The life-time and 12-month odds of being diagnosed with SUD in subjects with OCD are significantly higher than the odds of SUD for people without a psychiatric disorder. In men, the co-occurrence of substance dependence and OCD is significantly higher than the co-occurrence of substance dependence and other psychiatric disorders, whereas in women this co-occurrence does not differ significantly.

CONCLUSIONS:

  The co-occurrence of substance dependence in obsessive-compulsive disorder is higher than the co-occurrence of substance dependence in other non-obsessive-compulsive disorder DSM disorders, especially in men.

© 2011 The Authors, Addiction © 2011 Society for the Study of Addiction.

PMID:
21714825
[PubMed - indexed for MEDLINE]
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