Fertil Steril. 2011 Jun 30;95(8):2439-48.e1-5.

The Y chromosome in the era of intracytoplasmic sperm injection: a personal review.

Source

Infertility Center of St. Louis, St. Luke's Hospital, St. Louis, Missouri 63017, USA. silber@infertile.com

Abstract

The Y chromosome contains 60 multicopy genes composed of nine different gene families concentrated in regions of multiple repeat sequences called amplicons arranged in mirror images called palindromes. This pattern is susceptible to deletions caused by homologous recombination with itself, and can explain the presence of small numbers of sperm in otherwise azoospermic men.

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A novel partial deletion of the Y chromosome azoospermia factor c region is caused by non-homologous recombination between palindromes and may be associated with increased sperm counts. [Hum Reprod. 2011]
A novel partial deletion of the Y chromosome azoospermia factor c region is caused by non-homologous recombination between palindromes and may be associated with increased sperm counts.
Noordam MJ, van Daalen SK, Hovingh SE, Korver CM, van der Veen F, Repping S. Hum Reprod. 2011 Mar; 26(3):713-23. Epub 2011 Jan 11.
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Hung AJ, King P, Schlegel PN. J Urol. 2007 Aug; 178(2):608-12; discussion 612. Epub 2007 Jun 13.
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Review The Y chromosome and male infertility.
Sadeghi-Nejad H, Oates RD. Curr Opin Urol. 2008 Nov; 18(6):628-32.

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The Y chromosome in the era of intracytoplasmic sperm injection: a personal revi...
The Y chromosome in the era of intracytoplasmic sperm injection: a personal review.
Fertil Steril. 2011 Jun 30 ;95(8):2439-48.e1-5.

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The Y chromosome in the era of intracytoplasmic sperm injection: a personal review.

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