Adipocytokines, gut hormones and growth factors in anorexia nervosa

Clin Chim Acta. 2011 Sep 18;412(19-20):1702-11. doi: 10.1016/j.cca.2011.06.007. Epub 2011 Jun 15.

Abstract

Anorexia nervosa is a complex eating disorder of unknown etiology which affects adolescent girls and young women and leads to chronic malnutrition. Clinical manifestations of prolonged semistarvation include a variety of physical features and psychiatric disorders. The study of different biological factors involved in the pathophysiology of anorexia nervosa is an area of active interest. In this review we have described the role of adipocytokines, neurotrophins, peptides of the gastrointestinal system and growth factors in appetite regulation, energy balance and insulin sensitivity in anorexia nervosa patients.

Publication types

  • Review

MeSH terms

  • Adipokines / physiology*
  • Anorexia Nervosa / physiopathology*
  • Ghrelin / physiology*
  • Humans
  • Intercellular Signaling Peptides and Proteins / physiology*

Substances

  • Adipokines
  • Ghrelin
  • Intercellular Signaling Peptides and Proteins