Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Int J Environ Res Public Health. 2011 Apr;8(4):1141-9. doi: 10.3390/ijerph8041141. Epub 2011 Apr 15.

The dynamics of norovirus outbreak epidemics: recent insights.

Author information

  • 1Victorian Infectious Diseases Reference Laboratory, 10 Wreckyn Street, North Melbourne, Victoria 3051, Australia.

Abstract

Noroviruses are a major cause of gastroenteritis outbreaks worldwide. Norovirus outbreaks frequently occur as epidemics which appear to be related to both genetic and environmental factors. This review considers recent progress in understanding these factors. The norovirus genome undergoes continuous change and this appears to be important in the persistence of the virus in the community. Studies on the common GII.4 genotype have shown that some norovirus outbreak epidemics involving this genotype are correlated with specific changes in the genome. In contrast to the growing understanding of the role of genetic factors in norovirus outbreak epidemics, the role of environmental factors is less well understood. Topics reviewed here include long term excretion of norovirus in some individuals, long term survivability of norovirus in the environment, the role of meteorological factors in the control of norovirus outbreaks and the possible zoonotic transmission of the virus.

KEYWORDS:

environmental factors; epidemics; genetic factors; norovirus; outbreaks

PMID:
21695033
[PubMed - indexed for MEDLINE]
PMCID:
PMC3118882
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
    Loading ...
    Write to the Help Desk