Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Clin Liver Dis. 2011 May;15(2):223-43, vii-x. doi: 10.1016/j.cld.2011.03.006.

The global epidemiology of hepatocellular carcinoma: present and future.

Author information

  • 1Division of Cancer Epidemiology and Genetics, National Cancer Institute, EPS-5020, 6120 Executive Boulevard, Rockville, MD 20852-7234, USA. mcglynnk@mail.nih.gov

Abstract

The global risk of hepatocellular carcinoma (HCC) has been largely driven by hepatitis B virus (HBV) infection for the past century, along with hepatitis C virus (HCV), aflatoxin, excessive alcohol consumption, and obesity/diabetes. The dominant effect of HBV on global HCC risk should decline as the population vaccinated against HBV grows older. Infection with HCV is also expected to decline. Projections of HCV-related HCC rates remaining high for another 30 years may be overly pessimistic. Alcohol may be less of a factor in HCC in coming years. However, obesity and diabetes may become even more important risk factors for HCC.

Copyright © 2011. Published by Elsevier Inc.

PMID:
21689610
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk