Warning: The NCBI web site requires JavaScript to function. more...

My NCBI Sign In

Result Filters

IEEE Rev Biomed Eng. 2009;2:110-135.

Computational Models for Neuromuscular Function.

Valero-Cuevas FJ, Hoffmann H, Kurse MU, Kutch JJ, Theodorou EA.

Abstract

Computational models of the neuromuscular system hold the potential to allow us to reach a deeper understanding of neuromuscular function and clinical rehabilitation by complementing experimentation. By serving as a means to distill and explore specific hypotheses, computational models emerge from prior experimental data and motivate future experimental work. Here we review computational tools used to understand neuromuscular function including musculoskeletal modeling, machine learning, control theory, and statistical model analysis. We conclude that these tools, when used in combination, have the potential to further our understanding of neuromuscular function by serving as a rigorous means to test scientific hypotheses in ways that complement and leverage experimental data.

PMID:: 21687779; [PubMed]
PMCID:: PMC3116649

Free PMC Article

Images from this publication.See all images (10) Free text

Fig. 2

Fig. 4

Fig. 6

Fig. 8

Fig. 10

Fig. 1

Fig. 3

Fig. 5

Fig. 7

Fig. 9

Grant Support

Grant Support

LinkOut - more resources

Full Text Sources

Supplemental Content

Icon for PubMed Central

Save items

loading

Related citations in PubMed

Review A computational approach to prefrontal cortex, cognitive control and schizophrenia: recent developments and current challenges. [Philos Trans R Soc Lond B Biol...]
Review A computational approach to prefrontal cortex, cognitive control and schizophrenia: recent developments and current challenges.
Cohen JD, Braver TS, O'Reilly RC. Philos Trans R Soc Lond B Biol Sci. 1996 Oct 29; 351(1346):1515-27.
Comparative effectiveness research: Challenges for medical journals. [Cochrane Database Syst Rev. 2010]
Comparative effectiveness research: Challenges for medical journals.
Sox HC, Helfand M, Grimshaw J, Dickersin K, Tovey D, Knottnerus JA, Tugwell P. Cochrane Database Syst Rev. 2010 Apr 27; 8:ED000003. Epub 2010 Apr 27.
Optimality in neuromuscular systems. [Conf Proc IEEE Eng Med Biol So...]
Optimality in neuromuscular systems.
Theodorou E, Valero-Cuevas FJ. Conf Proc IEEE Eng Med Biol Soc. 2010; 2010:4510-6.
Computational modeling of epilepsy for an experimental neurologist. [Exp Neurol. 2012]
Computational modeling of epilepsy for an experimental neurologist.
Holt AB, Netoff TI. Exp Neurol. 2012 May 14; . Epub 2012 May 14.
Review Computational modeling of cardiac ventricular action potentials in rat and mouse: review. [Jpn J Physiol. 2004]
Review Computational modeling of cardiac ventricular action potentials in rat and mouse: review.
Demir SS. Jpn J Physiol. 2004 Dec; 54(6):523-30.

See reviews... See all...

Cited by 2 PubMed Central articles

Challenges and new approaches to proving the existence of muscle synergies of neural origin. [PLoS Comput Biol. 2012]
Challenges and new approaches to proving the existence of muscle synergies of neural origin.
Kutch JJ, Valero-Cuevas FJ. PLoS Comput Biol. 2012 May; 8(5):e1002434. Epub 2012 May 3.
A single muscle's multifunctional control potential of body dynamics for postural control and running. [Philos Trans R Soc Lond B Biol...]
A single muscle's multifunctional control potential of body dynamics for postural control and running.
Sponberg S, Spence AJ, Mullens CH, Full RJ. Philos Trans R Soc Lond B Biol Sci. 2011 May 27; 366(1570):1592-605.

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
References for this PMC Article
Citation referenced in PubMed article. Only valid for PubMed citations that are also in PMC.
Free in PMC
Free full text articles in PMC
Cited in PMC
Full-text articles in the PubMed Central Database that cite the current articles.

Recent activity

Clear Turn Off Turn On

Computational Models for Neuromuscular Function.
Computational Models for Neuromuscular Function.
IEEE Rev Biomed Eng. 2009;2:110-135.

PubMed
Peripheral neuropathy in xeroderma pigmentosum.
Peripheral neuropathy in xeroderma pigmentosum.
Brain. 1990 Aug ;113 ( Pt 4):1025-44.

PubMed
Use of a rabbit soft tissue chamber model to investigate campylobacter jejuni-ho...
Use of a rabbit soft tissue chamber model to investigate campylobacter jejuni-host interactions.
Front Microbiol. 2010 ;1:126. Epub 2010 Nov 16 .

PubMed
Mapping the risk of anaemia in preschool-age children: the contribution of malnu...
Mapping the risk of anaemia in preschool-age children: the contribution of malnutrition, malaria, and helminth infections in West Africa.
PLoS Med. 2011 Jun ;8(6):e1000438. Epub 2011 Jun 7 .

PubMed
Conserved CDC20 cell cycle functions are carried out by two of the five isoforms...
Conserved CDC20 cell cycle functions are carried out by two of the five isoforms in Arabidopsis thaliana.
PLoS One. 2011 ;6(6):e20618. Epub 2011 Jun 8 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...

You are here: NCBI > Literature > PubMed

Write to the Help Desk