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Int J Dev Neurosci. 2012 May;30(3):185-90. doi: 10.1016/j.ijdevneu.2011.05.009. Epub 2011 May 27.

Repeat traumatic brain injury in the developing brain.

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  • 1UCLA David Geffen School of Medicine, Department of Neurosurgery, United States.


The Center for Disease Control estimates that there are 1.7 million brain injuries in the US each year with 51% of these injuries occurring during periods of cerebral development. Among this population there is a growing population of individuals with repeat traumatic brain injury (RTBI). While the exact incidence is unknown, estimates range from 5.6 to 36% of the TBI population. This review summarizes the clinical problems/challenges and experimental research models that currently exist. It is intended to reveal the critical areas that need to be addressed so that age-relevant clinical management guidelines can be established to protect this population.

Published by Elsevier Ltd.

[PubMed - indexed for MEDLINE]
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