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Am J Public Health. 2011 Aug;101(8):e17-27. doi: 10.2105/AJPH.2010.300104. Epub 2011 Jun 16.

From controlled trial to community adoption: the multisite translational community trial.

Author information

  • 1Yale-Griffin Prevention Research Center, Derby, CT 06418, USA. david.katz@yale.edu

Abstract

Methods for translating the findings of controlled trials, such as the Diabetes Prevention Program, into real-world community application have not been clearly defined. A standardized research methodology for making and evaluating such a transition is needed. We introduce the multisite translational community trial (mTCT) as the research analog to the multisite randomized controlled trial. The mTCT is adapted to incorporate the principles and practices of community-based participatory research and the increased relevance and generalizability gained from diverse community settings. The mTCT is a tool designed to bridge the gap between what a clinical trial demonstrates can work in principle and what is needed to make it workable and effective in real-world settings. Its utility could be put to the test, in particular with practice-based research networks such as the Prevention Research Centers.

Comment in

PMID:
21680935
[PubMed - indexed for MEDLINE]
PMCID:
PMC3134505
Free PMC Article

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