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    Results: 15

    1.

    P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice.

    Furlan-Freguia C, Marchese P, Gruber A, Ruggeri ZM, Ruf W.

    J Clin Invest. 2011 Jul;121(7):2932-44. doi: 10.1172/JCI46129. Epub 2011 Jun 13.

    PMID:
    21670495
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice.

    Weber C, Meiler S, Döring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Förster I, Zenke M, Hieronymus T, Junt T, Zernecke A.

    J Clin Invest. 2011 Jul;121(7):2898-910. doi: 10.1172/JCI44925.

    PMID:
    21633167
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    Absence of Stat1 in donor CD4⁺ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in mice.

    Ma H, Lu C, Ziegler J, Liu A, Sepulveda A, Okada H, Lentzsch S, Mapara MY.

    J Clin Invest. 2011 Jul;121(7):2554-69. doi: 10.1172/JCI43706. Epub 2011 Jun 13.

    PMID:
    21670504
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Effective posttransplant antitumor immunity is associated with TLR-stimulating nucleic acid-immunoglobulin complexes in humans.

    Lin Y, Zhang L, Cai AX, Lee M, Zhang W, Neuberg D, Canning CM, Soiffer RJ, Alyea EP, Ritz J, Hacohen N, Means TK, Wu CJ.

    J Clin Invest. 2011 Apr;121(4):1574-84. doi: 10.1172/JCI44581. Epub 2011 Mar 14.

    PMID:
    21403403
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    5.

    Human prostate cancer metastases target the hematopoietic stem cell niche to establish footholds in mouse bone marrow.

    Shiozawa Y, Pedersen EA, Havens AM, Jung Y, Mishra A, Joseph J, Kim JK, Patel LR, Ying C, Ziegler AM, Pienta MJ, Song J, Wang J, Loberg RD, Krebsbach PH, Pienta KJ, Taichman RS.

    J Clin Invest. 2011 Apr;121(4):1298-312. doi: 10.1172/JCI43414. Epub 2011 Mar 23.

    PMID:
    21436587
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    6.

    Murine erythroid short-term radioprotection requires a BMP4-dependent, self-renewing population of stress erythroid progenitors.

    Harandi OF, Hedge S, Wu DC, McKeone D, Paulson RF.

    J Clin Invest. 2010 Dec;120(12):4507-19. doi: 10.1172/JCI41291. Epub 2010 Nov 8.

    PMID:
    21060151
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    7.

    Antagonism of the chemokine Ccl5 ameliorates experimental liver fibrosis in mice.

    Berres ML, Koenen RR, Rueland A, Zaldivar MM, Heinrichs D, Sahin H, Schmitz P, Streetz KL, Berg T, Gassler N, Weiskirchen R, Proudfoot A, Weber C, Trautwein C, Wasmuth HE.

    J Clin Invest. 2010 Nov;120(11):4129-40. doi: 10.1172/JCI41732. Epub 2010 Oct 18.

    PMID:
    20978355
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    8.

    Mammalian target of rapamycin activation underlies HSC defects in autoimmune disease and inflammation in mice.

    Chen C, Liu Y, Liu Y, Zheng P.

    J Clin Invest. 2010 Nov;120(11):4091-101. doi: 10.1172/JCI43873. Epub 2010 Oct 25. Erratum in: J Clin Invest. 2010 Dec 1;120(12):4583.

    PMID:
    20972332
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    9.

    Nonhematopoietic antigen blocks memory programming of alloreactive CD8+ T cells and drives their eventual exhaustion in mouse models of bone marrow transplantation.

    Flutter B, Edwards N, Fallah-Arani F, Henderson S, Chai JG, Sivakumaran S, Ghorashian S, Bennett CL, Freeman GJ, Sykes M, Chakraverty R.

    J Clin Invest. 2010 Nov;120(11):3855-68. doi: 10.1172/JCI41446. Epub 2010 Oct 18.

    PMID:
    20978352
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    10.

    HSP90 is a therapeutic target in JAK2-dependent myeloproliferative neoplasms in mice and humans.

    Marubayashi S, Koppikar P, Taldone T, Abdel-Wahab O, West N, Bhagwat N, Caldas-Lopes E, Ross KN, Gönen M, Gozman A, Ahn JH, Rodina A, Ouerfelli O, Yang G, Hedvat C, Bradner JE, Chiosis G, Levine RL.

    J Clin Invest. 2010 Oct;120(10):3578-93. doi: 10.1172/JCI42442. Epub 2010 Sep 13.

    PMID:
    20852385
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    11.

    Alloantigen expression on non-hematopoietic cells reduces graft-versus-leukemia effects in mice.

    Asakura S, Hashimoto D, Takashima S, Sugiyama H, Maeda Y, Akashi K, Tanimoto M, Teshima T.

    J Clin Invest. 2010 Jul;120(7):2370-8. doi: 10.1172/JCI39165. Epub 2010 Jun 7.

    PMID:
    20530875
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    12.

    Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice.

    Olivera A, Eisner C, Kitamura Y, Dillahunt S, Allende L, Tuymetova G, Watford W, Meylan F, Diesner SC, Li L, Schnermann J, Proia RL, Rivera J.

    J Clin Invest. 2010 May;120(5):1429-40. doi: 10.1172/JCI40659. Epub 2010 Apr 19.

    PMID:
    20407207
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    13.

    Pivotal role for glycogen synthase kinase-3 in hematopoietic stem cell homeostasis in mice.

    Huang J, Zhang Y, Bersenev A, O'Brien WT, Tong W, Emerson SG, Klein PS.

    J Clin Invest. 2009 Dec;119(12):3519-29.

    PMID:
    19959876
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    14.

    PKCtheta is required for alloreactivity and GVHD but not for immune responses toward leukemia and infection in mice.

    Valenzuela JO, Iclozan C, Hossain MS, Prlic M, Hopewell E, Bronk CC, Wang J, Celis E, Engelman RW, Blazar BR, Bevan MJ, Waller EK, Yu XZ, Beg AA.

    J Clin Invest. 2009 Dec;119(12):3774-86. doi: 10.1172/JCI39692. Epub 2009 Nov 9.

    PMID:
    19907075
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    15.

    The cytolytic molecules Fas ligand and TRAIL are required for murine thymic graft-versus-host disease.

    Na IK, Lu SX, Yim NL, Goldberg GL, Tsai J, Rao U, Smith OM, King CG, Suh D, Hirschhorn-Cymerman D, Palomba L, Penack O, Holland AM, Jenq RR, Ghosh A, Tran H, Merghoub T, Liu C, Sempowski GD, Ventevogel M, Beauchemin N, van den Brink MR.

    J Clin Invest. 2010 Jan;120(1):343-56. doi: 10.1172/JCI39395. Epub 2009 Dec 1.

    PMID:
    19955659
    [PubMed - indexed for MEDLINE]
    Free PMC Article

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