Source
Medical University of South Carolina, Charleston, SC, USA, murphypa@musc.edu.
Abstract
BACKGROUND:
Low levels of serum 25-hydroxyvitamin D (25[OH]D), a reliable measurement of vitamin D, have been implicated in several mood disorders. To date, studies exploring the relationship between vitamin D and postpartum depression are absent from the literature.
OBJECTIVES:
To determine whether a relationship exists between symptoms associated with postpartum depression and vitamin D levels and to determine if serum 25(OH) D levels can predict the incidence of symptoms associated with postpartum depression.
STUDY DESIGN:
An exploratory, descriptive study using a convenience sample of 97 postpartum women attending seven monthly visits. Women provided serum 25(OH)D samples and completed the Edinburgh Postpartum Depression Scale (EPDS) at each visit.
RESULTS:
A significant relationship over time was found between low 25(OH)D levels and high EPDS scores, indicative of postpartum depression.
CONCLUSIONS:
Future rigorous studies investigating vitamin D and postpartum depression are warranted with larger sample sizes using confirmatory methods to diagnose postpartum depression.