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F1000 Biol Rep. 2011;3:8. doi: 10.3410/B3-8. Epub 2011 Apr 1.

New tools in membrane protein determination.

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  • 1Department of Biochemistry & Biophysics, University of California San Francisco, S-412C Genentech Hall, 600 16th Street, San Francisco, CA 94158-2517 USA.


The determination of membrane structures presents the structural biologist with many challenges; however, the last two years have seen major advances in our ability to resolve these structures at atomic resolution. My goal here is to summarize some of the most recent advances that have enhanced our prospects for understanding membrane proteins at the level of atomic structure.

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