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Clin Vaccine Immunol. 2011 Aug;18(8):1391-4. doi: 10.1128/CVI.00403-10. Epub 2011 Jun 8.

Multicentric evaluation of new commercial enzyme immunoassays for the detection of immunoglobulin M and total antibodies against hepatitis A virus.

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  • 1Microbiology Section, Department of Pathology and Laboratory Medicine, University of Parma, Viale Antonio Gramsci 14, 43126 Parma, Italy. mariacristina.arcangeletti@unipr.it

Abstract

A multicentric clinical study was conducted on representative sera from 1,738 European and U.S. subjects for the evaluation of new anti-hepatitis A virus enzyme immunoassays from Bio-Rad Laboratories. Comparison with reference DiaSorin S.p.A. tests confirmed the good performance of Bio-Rad assays (99.85% and 99.47% overall agreement in detecting total antibodies and IgM, respectively).

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