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Development. 2011 Jul;138(13):2845-53. doi: 10.1242/dev.063594.

The GUDMAP database--an online resource for genitourinary research.

Author information

  • 1MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK. sharding@hgu.mrc.ac.uk

Abstract

The GenitoUrinary Development Molecular Anatomy Project (GUDMAP) is an international consortium working to generate gene expression data and transgenic mice. GUDMAP includes data from large-scale in situ hybridisation screens (wholemount and section) and microarray gene expression data of microdissected, laser-captured and FACS-sorted components of the developing mouse genitourinary (GU) system. These expression data are annotated using a high-resolution anatomy ontology specific to the developing murine GU system. GUDMAP data are freely accessible at www.gudmap.org via easy-to-use interfaces. This curated, high-resolution dataset serves as a powerful resource for biologists, clinicians and bioinformaticians interested in the developing urogenital system. This paper gives examples of how the data have been used to address problems in developmental biology and provides a primer for those wishing to use the database in their own research.

PMID:
21652655
[PubMed - indexed for MEDLINE]
PMCID:
PMC3188593
Free PMC Article

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