Abstract
Background:
Eosinophilic gastrointestinal disorders (EGIDs) are disorders characterized by primary eosinophil inflammation in the gastrointestinal tract. There are a small number of reports of eosinophil infiltration in gastrointestinal tracts presenting as EGIDs in infants. In this study, we present Japanese cases of EGIDs in infants.
Methods:
Five patients diagnosed with or strongly suspected to have EGIDs in our hospital from 2008 to 2010 were reviewed. Radiographic contrast enema examinations and/or endoscopies were performed in 4 and 3 patients, respectively.
Results:
There were patients with eosinophilic colitis (1 suspected and 2 biopsy-proven), a patient who was suspected of having allergic eosinophilic enterocolitis, and a patient with eosinophilic gastroenteritis associated with pediatric hypereosinophilic syndrome.
Conclusions:
The causes and clinical findings of patients with intestinal eosinophil inflammation vary. Therefore, deliberate examination and observation are important for patients with infantile EGID.
Copyright © 2011 S. Karger AG, Basel.
Publication types
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Case Reports
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Research Support, Non-U.S. Gov't
MeSH terms
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Colon / pathology
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Congenital Abnormalities / pathology
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Constriction, Pathologic / pathology
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Eczema / complications
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Enteritis* / blood
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Enteritis* / complications
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Enteritis* / diagnosis
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Enteritis* / etiology
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Enteritis* / pathology
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Enteritis* / therapy
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Eosinophilia* / blood
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Eosinophilia* / complications
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Eosinophilia* / diagnosis
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Eosinophilia* / etiology
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Eosinophilia* / pathology
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Eosinophilia* / therapy
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Eosinophils / pathology
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Feces / cytology
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Female
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Gastric Mucosa / pathology
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Gastritis* / blood
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Gastritis* / complications
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Gastritis* / diagnosis
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Gastritis* / etiology
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Gastritis* / pathology
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Gastritis* / therapy
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Humans
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Hypereosinophilic Syndrome / blood
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Hypereosinophilic Syndrome / complications
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Hypereosinophilic Syndrome / pathology
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Immunoglobulin E / blood
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Immunoglobulin E / immunology
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Infant
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Infant, Newborn
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Intestinal Mucosa / pathology
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Japan
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Male
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Milk Hypersensitivity / complications
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Milk Hypersensitivity / immunology
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Myocarditis / complications
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Occult Blood
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Prednisolone / therapeutic use
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Rectum / pathology
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Syndrome
Substances
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Immunoglobulin E
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Prednisolone