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MDC1 is ubiquitylated on its tandem BRCT domain and directly binds RAP80 in a UBC13-dependent manner.
Strauss C, Halevy T, Macarov M, Argaman L, Goldberg M.
DNA Repair (Amst). 2011 Aug 15;10(8):806-14. Epub 2011 May 31.
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Disassembly of MDC1 foci is controlled by ubiquitin-proteasome-dependent degradation.
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