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J Am Med Inform Assoc. 2011 Sep-Oct;18(5):645-51. doi: 10.1136/amiajnl-2010-000034. Epub 2011 May 25.

Evaluation of the NCPDP Structured and Codified Sig Format for e-prescriptions.

Author information

  • 1RAND Corporation, Boston, Massachusetts 02116, USA. hliu@rand.org

Abstract

OBJECTIVE:

To evaluate the ability of the structure and code sets specified in the National Council for Prescription Drug Programs Structured and Codified Sig Format to represent ambulatory electronic prescriptions.

DESIGN:

We parsed the Sig strings from a sample of 20,161 de-identified ambulatory e-prescriptions into variables representing the fields of the Structured and Codified Sig Format. A stratified random sample of these representations was then reviewed by a group of experts. For codified Sig fields, we attempted to map the actual words used by prescribers to the equivalent terms in the designated terminology.

MEASUREMENTS:

Proportion of prescriptions that the Format could fully represent; proportion of terms used that could be mapped to the designated terminology.

RESULTS:

The fields defined in the Format could fully represent 95% of Sigs (95% CI 93% to 97%), but ambiguities were identified, particularly in representing multiple-step instructions. The terms used by prescribers could be codified for only 60% of dose delivery methods, 84% of dose forms, 82% of vehicles, 95% of routes, 70% of sites, 33% of administration timings, and 93% of indications.

LIMITATIONS:

The findings are based on a retrospective sample of ambulatory prescriptions derived mostly from primary care physicians.

CONCLUSION:

The fields defined in the Format could represent most of the patient instructions in a large prescription sample, but prior to its mandatory adoption, further work is needed to ensure that potential ambiguities are addressed and that a complete set of terms is available for the codified fields.

PMID:
21613642
[PubMed - indexed for MEDLINE]
PMCID:
PMC3168301
Free PMC Article

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