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    Int J Urol. 2011 Jul;18(7):521-4. doi: 10.1111/j.1442-2042.2011.02777.x. Epub 2011 May 23.

    Clinical course of vesicoureteral reflux in patients with hypospadias.

    Source

    Department of Urology, Urological Science Institute, Yonsei University College of Medicine, Seoul, Korea. swhan@yuhs.ac

    Abstract

    OBJECTIVES:

    The prevalence of vesicoureteral reflux (VUR) in hypospadic patients is reportedly higher than in healthy children. We investigated the prevalence and the clinical course of VUR in hypospadic patients.

    METHODS:

    We carried out intraoperative cystography to detect VUR in 338 patients who underwent hypospadias repair. Age, severity of hypospadias and the presence of VUR were investigated. A dimercaptosuccinic acid renal scan and follow-up voiding cystourethrography (VCUG) were carried out if VUR was detected.

    RESULTS:

    VUR was detected in 41 patients (12.1%). Of 156 patients who were younger than 1 year-of-age, 34 (21.8%) were found to have VUR. The prevalence of VUR was significantly higher in patients younger than 1year (P<0.001), but was not associated with hypospadias type (P=0.212). The reflux grades were I, II and III in 6, 52 and 1 renal units, respectively. Renal scarring was shown in one of 36 patients. Follow-up VCUG was carried out in 30 patients at a mean of 14.28±3.89months, and reflux resolved in 27 and improved from grade II to grade I in three patients.

    CONCLUSIONS:

    Although its prevalence is higher in hypospadic children than in healthy children, it is not necessary to screen for VUR in hypospadic patients, because it is likely to be low-grade and to resolve in most cases.

    © 2011 The Japanese Urological Association.

    PMID:
    21605171
    [PubMed - indexed for MEDLINE]

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