Format

Send to:

Choose Destination
See comment in PubMed Commons below
Clin Pharmacol Ther. 2011 Jun;89(6):784-5. doi: 10.1038/clpt.2011.30.

The phenotype standardization project: improving pharmacogenetic studies of serious adverse drug reactions.

Author information

  • 1Wolfson Centre for Personalised Medicine, University of Liverpool, Liverpool, UK. munirp@liv.ac.uk

Abstract

The ability to predict the risk for serious drug-induced adverse reactions first requires a large patient database for characterization and validation of genetic markers. The Phenotype Standardization Project (PSP) was initiated to standardize phenotypic definitions, thereby facilitating much-needed recruitment without sacrificing the reliability of patient classification. Three phenotypes have been considered in this initial phase: drug-induced liver injury, drug-induced skin injury, and drug-induced torsade de pointes.

PMID:
21593754
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for John Wiley & Sons, Inc.
    Loading ...
    Write to the Help Desk