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Nat Immunol. 2011 Jun;12(6):522-4. doi: 10.1038/ni.2040.

Fox factors fight over T cell quiescence.

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  • 1Center for Immunology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.

Abstract

The transcription factor Foxp1 helps maintain the quiescence of naive T cells by inhibiting IL-7Rα expression and diminishing signaling by the kinase Erk.

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PMID:
21587312
[PubMed - indexed for MEDLINE]
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