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Appl Physiol Nutr Metab. 2011 Jun;36(3):419-22. doi: 10.1139/h11-014. Epub 2011 May 16.

Effect of creatine supplementation on measured glomerular filtration rate in postmenopausal women.

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  • 1Division of Rheumatology, School of Medicine, University of São Paulo, São Paulo, Brazil.

Abstract

We aimed to investigate whether creatine supplementation affects the measured glomerular filtration rate in postmenopausal women (age, 58 ± 3 years). Subjects were randomly assigned to receive either creatine (20 g·day(-1) for 1 week and 5 g·day(-1) thereafter) or a placebo. Kidney function was assessed at baseline and after 12 weeks. [(51)Cr]EDTA clearance remained unchanged (CR-PRE: 86.16 ± 14.36 mL·min(-1) per 1.73 m(2), POST: 87.25 ± 17.60 mL·min(-1) per 1.73 m(2); PL-PRE: 85.15 ± 8.54 mL·min(-1) per 1.73 m(2), POST: 87.18 ± 9.64 mL·min(-1) per 1.73 m(2); p = 0.81). Thus, we concluded that creatine supplementation does not affect glomerular filtration rate in postmenopausal women.

PMID:
21574777
[PubMed - indexed for MEDLINE]
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