Display Settings:

Format

Send to:

Choose Destination
See comment in PubMed Commons below
Pol J Pathol. 2011;62(1):60-4.

A case of prostatic adenocarcinoma with Paneth cell-like appearance.

Author information

  • 1Department of Pathology, Tohoku University School of Medicine, Sendai, Japan. yasu-naka@patholo2.med.tohoku.ac.jp

Abstract

Paneth cell-like appearance of prostatic carcinoma cells with eosinophilic cytoplasmic granules is rarely reported, and is known to be associated with neuroendocrine differentiation of carcinoma cells. We report a case of prostatic adenocarcinoma with Paneth cell-like appearance that was localized next to conventional adenocarcinoma, and demonstrate its neuroendocrine differentiation by using immunohistochemical analysis. Paneth cell-like appearance of prostatic carcinoma cells should be recognized and considered as a sign of neuroendocrine differentiation due to the possible association with resistance to hormone therapy.

PMID:
21574107
[PubMed - indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Icon for Termedia Publishing House Ltd.
    Loading ...
    Write to the Help Desk