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Indian J Dermatol. 2011 Jan;56(1):79-81. doi: 10.4103/0019-5154.77559.

Giant melanoacanthoma mimicking malignant melanoma.

Author information

  • 1Department of Dermatology, Venerology, Leprology, M.G.M. Medical College and L.S.K. Hospital, Kishanganj, Bihar, India.

Abstract

Melanoacanthoma denotes a rare variant of pigmented seborrheic keratosis. A 65-year-old male farmer had pigmented, verrucous, itchy, highly painful, progressively growing irregularly oval plaque on left side of lower back for the past five years. The indurated lesion, measuring maximum diameter 10 cm × 5 cm, had no discharge, bleeding, ulceration, or associated lymphadenopathy. Dermoscopy showed regular pigmentary network and cribiform pattern of ridges without any feature of malignant melanoma. Histopathology showed well-defined islands of basaloid cells interspersed with large and richly dendritic melanocytes. The lesion was totally excised followed by skin grafting. Our patient was unique in its massive size and clinical resemblance with malignant melanoma. The diagnosis was confirmed by dermoscopy and skin biopsy.

KEYWORDS:

Melanoacanthoma; dermoscopy; malignant melanoma; melanoma; pigmented seborrheic keratosis; seborrheic keratosis

PMID:
21572799
[PubMed]
PMCID:
PMC3088943
Free PMC Article

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