Mini Rev Med Chem. 2011 May 16. [Epub ahead of print]

Stem Cell-Mediated Delivery of Therapies in the Treatment of Glioma.

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Istituto Nazionale Ricerca Cancro, Molecular Mutagenesis & DNA Repair Unit, Genova, Italy. guido.frosina@istge.it.

Abstract

High grade gliomas can be seldom controlled, due to the infiltrative nature of these tumors and the presence of cell populations resistant to radio- and chemotherapy. Current research aims to develop novel therapeutic approaches to track and eliminate the disseminated glioma-driving cells. Selected delivery of therapeutic agents taking advantage of the tropism of normal stem cells for glioma cells might be one.

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Stem Cell-Mediated Delivery of Therapies in the Treatment of Glioma.
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Stem Cell-Mediated Delivery of Therapies in the Treatment of Glioma.

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