Dig Dis Sci. 2011 Nov;56(11):3382-5. Epub 2011 May 11.

Focal fat masquerading as malignancy in the liver graft of a post-transplant patient.

Patrick CM, Hayashi PH, Kozlowski T, Greene KG, Semelka RC, Barritt AS 4th.

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Department of Medicine, University of North Carolina, Chapel Hill, NC 27599-7080, USA.

Abstract

BACKGROUND AND AIMS:

Liver failure from non-alcoholic fatty liver disease (NAFLD) is an increasing indication for liver transplant and recurrence of fatty liver in transplanted grafts has been documented. Herein is described an atypical recurrence of steatosis as a de novo focal fatty lesion that mimicked a more ominous cancerous lesion. This presentation of recurrent NAFLD has not previously been described in the literature.

METHODS:

Chart review.

RESULTS:

Biopsy of an atypical lesion was found to be focal fat with surrounding steatohepatitis.

CONCLUSIONS:

Non-alcoholic fatty liver disease may recur after liver transplant and manifest as a focal fatty lesion. It is important to catalogue the atypical presentations of the increasingly common NAFLD developing in transplanted livers.

PMID:: 21559737; [PubMed - indexed for MEDLINE]
PMCID:: PMC3308147; [Available on 2012/11/1]

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1KL2-RR025746-03/RR/NCRR NIH HHS/United States

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Liver Transplantation - MedlinePlus Health Information

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