Neurol Sci. 2011 May;32 Suppl 1:S85-8.

Migraine and depression: common pathogenetic and therapeutic ground?

Moschiano F, D'Amico D, Canavero I, Pan I, Micieli G, Bussone G.

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National Institute of Neurology, IRCCS C. Mondino Foundation, Via Mondino 2, 27100 Pavia, Italy. franca.moschiano@mondino.it

Abstract

Migraine and depression are recognized as comorbid disorders on the basis of several epidemiological data and on the possibility of shared mechanisms. On the other hand, there is a lack of studies concerning therapeutic strategies in patients with this comorbidity. The aim of this paper is to briefly review the literature about the migraine and depression comorbidity and on the putative common neurobiological mechanisms, as well to discuss the possible therapeutic options in treating patients with both disorders.

PMID:: 21533720; [PubMed - indexed for MEDLINE]

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