A new, blue gene highlights glutamate and hippocampus in depression

Heike Tost; Andreas Meyer-Lindenberg

doi:10.1016/j.neuron.2011.04.008

A new, blue gene highlights glutamate and hippocampus in depression

Neuron. 2011 Apr 28;70(2):171-2. doi: 10.1016/j.neuron.2011.04.008.

Authors

Heike Tost¹, Andreas Meyer-Lindenberg

Affiliation

¹ Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, University of Heidelberg, Medical Faculty Mannheim, Mannheim, Germany.

PMID: 21521605
DOI: 10.1016/j.neuron.2011.04.008

Abstract

Depression is a common and debilitating psychiatric syndrome with a complex risk architecture marked by interacting genetic and environmental factors. In this issue of Neuron, the study by Kohli et al. (2011) reports a novel genome-wide supported risk variant for depression that affects hippocampal gene expression, anatomy, and biochemistry.

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