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Graefes Arch Clin Exp Ophthalmol. 2011 Oct;249(10):1515-8. doi: 10.1007/s00417-011-1684-y. Epub 2011 Apr 26.

Titanium back plate for a PMMA keratoprosthesis: clinical outcomes.

Author information

  • 1Cornea Service, Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA.

Abstract

BACKGROUND/PURPOSE:

To compare the rate of retroprosthetic membrane (RPM) formation in Boston Keratoprosthesis (BKPro) with polymethyl methacrylate (PMMA) versus titanium backplates.

DESIGN:

Retrospective comparative chart review.

METHODS:

Multicenter study population: a total of 78 eyes with keratoprosthesis implants with either PMMA or titanium backplates were included in the study. To be included in the study, all subjects had to have completed a minimum of 6-month follow-up period. Incidence of RPM development at 6-month postoperative period was noted across the study population. PMMA and titanium backplates were then compared by their rate of association with subsequent RPM.

RESULTS:

Twenty-three out of 55 eyes (41.8%) with PMMA backplates and three out of 23 eyes (13.0%) with titanium backplates had developed an RPM at 6 months after implantation. The titanium backplates were associated with significantly less RPM formation than PMMA backplates (p = 0.014, Chi-square test).

CONCLUSIONS:

Titanium seems to be associated with less RPM formation than PMMA when used as a material for the BKPro back plate.

PMID:
21519940
[PubMed - indexed for MEDLINE]
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