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Am J Ther. 2013 Jan;20(1):73-8. doi: 10.1097/MJT.0b013e31820b8846.

Tuberculosis infections and tumor necrosis factor alpha antagonists.

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  • 1Rush University Medical Center and John H. Stroger Jr Hospital of Cook County, Chicago, IL, USA.


The treatment of rheumatologic diseases with tumor necrosis factor-alpha antagonists has become common practice. Studies have demonstrated an increased risk of active tuberculosis with use of tumor necrosis factor-alpha antagonists. We aim to better define the risk of tuberculosis infection associated with tumor necrosis factor-alpha antagonists and to review the literature on the treatment of latent tuberculosis.

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