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J Psychosom Res. 2011 May;70(5):449-54. doi: 10.1016/j.jpsychores.2010.09.021. Epub 2010 Dec 16.

Psychiatric morbidity in HIV-positive subjects: a study from India.

Author information

  • 1Department of Psychiatry, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. drnaresh_pgi@yahoo.com

Abstract

OBJECTIVE:

To study the psychiatric morbidity in HIV-positive subjects.

DESIGN:

Cross-sectional.

METHODS:

The purposive sample included HIV-positive subjects not receiving antiretroviral therapy (HIV) (n=100). Rheumatoid arthritis (severe) subjects not receiving steroids or disease-modifying antirheumatic drugs (RA) (n=40) were included as a comparison group. The 12-item General Health Questionnaire in Hindi (GHQ) was used to screen the psychiatric morbidity in both groups. In GHQ-positive cases, psychiatric diagnoses were made using the Structured Clinical Interview for DSM-IV (SCID).

RESULTS:

The HIV group reported sexual contact as the commonest source of infection (58%) and had a lower age at onset (32.53 vs. 36.60 years, P=.011), shorter duration of illness (12.95 vs. 83.37 months, P<.001), lower GHQ score (28.3 vs. 30.15, P=.043), similar Mini Mental State Examination (MMSE) score (28.01 vs. 27.37, P=.093) and lower psychiatric morbidity by both GHQ (score >2) (52% vs. 85%) and current SCID diagnoses (45% vs. 60%, P=.021), as compared to the RA group. The HIV group also had a lower prevalence of psychiatric disorders (45% vs. 60%), mood disorders [24% vs. 52% including major depressive disorder (19% vs. 45%)] and anxiety disorders (1% vs. 2.5%), but a higher prevalence of substance use disorders (17% vs. 2.5%), adjustment disorders (7% vs. 5%) and psychotic disorders (1% vs. 0), as compared to the RA group.

CONCLUSION:

The high prevalence of psychiatric disorders, especially the mood disorders, in our HIV-positive subjects was generally similar to that reported from the rest of the world.

Copyright © 2010 Elsevier Inc. All rights reserved.

PMID:
21511075
[PubMed - indexed for MEDLINE]
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