Scand J Dent Res. 1990 Oct;98(5):434-41.

Alveolar ridge augmentation by osteoinduction in rats.

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Institute for Surgical Research, Rikshospitalet (The National Hospital), University of Oslo, Norway.

Abstract

The purpose of this study was to evaluate bone substitutes for alveolar ridge augmentation by osteoinduction. Allogenic, demineralized, and lyophilized dentin and bone was tested for osteoinductive properties in order to establish an experimental model for further studies. Implantations were performed subperiosteally on the premaxilla and heterotopically in the abdominal muscles of rats. Light microscopic evaluations revealed that all allogenic, demineralized, and lyophilized dentin and bone implants induced new bone formation. No inflammatory or foreign body reactions were observed.

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Alveolar ridge augmentation by osteoinduction in rats.

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