HIV Clin Trials. 2011 Mar-Apr;12(2):118-20.

Interferon successfully inhibited refractory cytomegalovirus infection and resulted in CD4+ T-cells increase in a patient with AIDS.

Abstract

We report on a young male HIV-positive patient with cytomegalovirus (CMV) retinitis who received HAART and ganciclovir but could not gain immune restoration. One and a half years later, his CMV reoccurred. He was treated again with ganciclovir treatment combined with foscarnet treatment but failed. Finally, he was treated with recombinant human interferon alpha-2b (IFN-α2b) alone and acquired sustained inhibition to CMV. His CD4+ T-cell count increased to 186 cell/mm3 and gained partial immune restoration. Retinitis progression has stopped.

PMID:: 21498155; [PubMed - indexed for MEDLINE]

Free full text

Publication Types, MeSH Terms, Substances

Publication Types

MeSH Terms

Substances

LinkOut - more resources

Full Text Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

High-dose (5000-microg) intravitreal ganciclovir combined with highly active antiretroviral therapy for cytomegalovirus retinitis in HIV-infected patients in Venezuela. [Eur J Ophthalmol. 2005]
High-dose (5000-microg) intravitreal ganciclovir combined with highly active antiretroviral therapy for cytomegalovirus retinitis in HIV-infected patients in Venezuela.
Arevalo JF, Garcia RA, Mendoza AJ. Eur J Ophthalmol. 2005 Sep-Oct; 15(5):610-8.
Characterization of reactivation of cytomegalovirus retinitis in patients healed after treatment with highly active antiretroviral therapy. [Retina. 2000]
Characterization of reactivation of cytomegalovirus retinitis in patients healed after treatment with highly active antiretroviral therapy.
Song MK, Karavellas MP, MacDonald JC, Plummer DJ, Freeman WR. Retina. 2000; 20(2):151-5.
Highly active antiretroviral therapy-related immune recovery in AIDS patients with cytomegalovirus retinitis. [Ophthalmology. 2000]
Highly active antiretroviral therapy-related immune recovery in AIDS patients with cytomegalovirus retinitis.
Macdonald JC, Karavellas MP, Torriani FJ, Morse LS, Smith IL, Reed JB, Freeman WR. Ophthalmology. 2000 May; 107(5):877-81; discussion 881-3.
Review Cytomegalovirus infection: the point in 2001. [HIV Med. 2001]
Review Cytomegalovirus infection: the point in 2001.
Salmon-Ceron D. HIV Med. 2001 Oct; 2(4):255-9.
Review CMV retinitis in the era of HAART. [Ocul Immunol Inflamm. 1999]
Review CMV retinitis in the era of HAART.
Cassoux N, Bodaghi B, Katlama C, LeHoang P. Ocul Immunol Inflamm. 1999 Dec; 7(3-4):231-5.

See reviews... See all...

Related information

Related Citations
Calculated set of PubMed citations closely related to the selected article(s) retrieved using a word weight algorithm. Related articles are displayed in ranked order from most to least relevant, with the “linked from” citation displayed first.
Substance (MeSH Keyword)
PubChem chemical substance (submitted) records that are classified under the same Medical Subject Headings (MeSH) controlled vocabulary as the current articles.

Recent activity

Clear Turn Off Turn On

Interferon successfully inhibited refractory cytomegalovirus infection and resul...
Interferon successfully inhibited refractory cytomegalovirus infection and resulted in CD4+ T-cells increase in a patient with AIDS.
HIV Clin Trials. 2011 Mar-Apr ;12(2):118-20.

PubMed
Preoxygenated hyperventilated hypocapnic apnea-induced radiation (PHAIR) in brea...
Preoxygenated hyperventilated hypocapnic apnea-induced radiation (PHAIR) in breast cancer patients.
Radiother Oncol. 2011 Aug ;100(2):231-5. Epub 2011 Apr 16 .

PubMed
High expression of cytoskeletal protein drebrin in TEL/AML1pos B-cell precursor ...
High expression of cytoskeletal protein drebrin in TEL/AML1pos B-cell precursor acute lymphoblastic leukemia identified by a novel monoclonal antibody.
Leuk Res. 2011 Aug ;35(8):1111-3. Epub 2011 Apr 16 .

PubMed
[Giant-cell tumor of the lower end of the radius treated by resection-arthrodesi...
[Giant-cell tumor of the lower end of the radius treated by resection-arthrodesis. Report of 9 cases].
Rev Chir Orthop Reparatrice Appar Mot. 1990 ;76(6):420-4.

PubMed
A novel optical method to assess cervical changes during pregnancy and use to ev...
A novel optical method to assess cervical changes during pregnancy and use to evaluate the effects of progestins on term and preterm labor.
Am J Obstet Gynecol. 2011 Jul ;205(1):82.e15-20. Epub 2011 Feb 23 .

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to: