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J Pregnancy. 2011;2011:928381. doi: 10.1155/2011/928381. Epub 2011 Mar 3.

The role of proteoglycans in contributing to placental thrombosis and fetal growth restriction.

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  • 1Level 7 Research Precinct, The Royal Women's Hospital, Locked Bag 300, Parkville, VIC 3052, Australia; Department of Obstetrics and Gynaecology, University of Melbourne, Parkville 3052, Australia. jo.said@thewomens.org.au

Abstract

Fetal growth restriction is an important pregnancy complication that has major consequences for the fetus and neonate as well as an increased risk of long-term morbidity extending into adulthood. The precise aetiology of most cases of fetal growth restriction is unknown although placental thrombosis is a common feature in many of these cases. This paper will outline the potential role of proteoglycans in contributing to placental thrombosis and fetal growth restriction.

PMID:
21490795
[PubMed - indexed for MEDLINE]
PMCID:
PMC3065915
Free PMC Article
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