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Epilepsy Behav. 2011 May;21(1):71-5. doi: 10.1016/j.yebeh.2011.03.005. Epub 2011 Apr 9.

Sleep characteristics of patients with epilepsy with pure sleep-related seizures.

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  • 1Epimer Epilepsy Center and Istanbul Faculty of Medicine, Department of Neurology, Istanbul University, Istanbul, Turkey.



Our aim was to investigate the clinical features and sleep characteristics of patients with pure sleep-related seizures.


Patients with pure sleep epilepsy were prospectively enrolled and their clinical, EEG, and MRI findings investigated. The Medical Outcomes Study Sleep Scale (MOS-SS) was administered after receiving consent.


Thirty-nine of 1401 consecutive patients (2.7%) with pure sleep-related seizures were included. Of these, 30 (76.9%) had epilepsy of unknown cause and 7 had epilepsy with known structural etiologies. Twenty-seven patients reported less than one seizure per month and 19 had been seizure free for at least 1 year. Thirty-four patients participated in our MOS-SS study. Comparison of sleep problems between those with epilepsy and healthy controls and between the subgroups with frequent and rare seizures did not reveal significant differences.


Patients with pure sleep seizures had mostly undetermined etiology usually with a good prognosis, and this rare condition did not seem to affect their sleep quality.

Copyright © 2011 Elsevier Inc. All rights reserved.

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