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J Pak Med Assoc. 2011 Apr;61(4):399-401.

Uterine rupture associated with the use of intra-vaginal misoprostol during second-trimester pregnancy termination.

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  • 1Gynecology and Obstetrics Unit-1, Holy Family Hospital, Rawalpindi, Pakistan.


Intravaginal Misoprostol is being used with excellent results for second trimester pregnancy termination, worldwide. However, there are many case reports of serious complications of uterine rupture in such cases, both in previously scarred as well as in unscarred uterus. In this report, we describe a case of uterine rupture in an unscarred uterus during second-trimester pregnancy termination with intravaginal misoprostol.

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