Hematol Oncol Stem Cell Ther. 2011;4(1):41-4.

AIDS-related sinonasal Burkitt lymphoma successfully treated with intensive chemotherapy regimen and high active antiretroviral therapy.

Werutsky G, de Carvalho GP, da Silva VD, Garicochea B.

Source

Department of Medical Oncology, Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil. gwerutsky@hotmail.com

Abstract

Burkitt lymphoma (BL) is the second most common AIDS-related lymphoma. Primary sinonasal BL in HIV patients is extremely rare and treatment data in this subset of patients is almost nonexistent. Recently, a few studies reported promising results treating HIV-associate BL with an intensive chemotherapy regimen. The use of highly active antiretroviral therapy (HAARTHAART) concomitantly with chemotherapy seems to improve patient outcomes, but this topic is still controversial due to potential drug interactions. We report a case of a 29-year old woman diagnosed with AIDS presenting with symptoms of chronic sinusitis. Subsequent investigation by CT scan and endoscopic biopsy discovered a sinonasal BL in an early stage. The patient was treated with intensive chemotherapy and HAARTHAART and achieved a complete remission and long-term immunologic recovery. This case report describes a rare entity whose natural history, treatment and prognosis is infrequently characterized in the medical literature.

PMID:: 21460606; [PubMed - indexed for MEDLINE]

LinkOut - more resources

Other Literature Sources

Labome Researcher Resource - ExactAntigen/Labome

Medical

Supplemental Content

Save items

Related citations in PubMed

Hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone and highly active antiretroviral therapy for patients with acquired immunodeficiency syndrome-related Burkitt lymphoma/leukemia. [Cancer. 2002]
Hyperfractionated cyclophosphamide, vincristine, doxorubicin, and dexamethasone and highly active antiretroviral therapy for patients with acquired immunodeficiency syndrome-related Burkitt lymphoma/leukemia.
Cortes J, Thomas D, Rios A, Koller C, O'Brien S, Jeha S, Faderl S, Kantarjian H. Cancer. 2002 Mar 1; 94(5):1492-9.
Successful treatment with modified CHOP-rituximab in pediatric AIDS-related advanced stage Burkitt lymphoma. [Pediatr Blood Cancer. 2008]
Successful treatment with modified CHOP-rituximab in pediatric AIDS-related advanced stage Burkitt lymphoma.
Crosswell HE, Bergsagel DJ, Yost R, Lew G. Pediatr Blood Cancer. 2008 Apr; 50(4):883-5.
Intensive chemotherapy with cyclophosphamide, doxorubicin, high-dose methotrexate/ifosfamide, etoposide, and high-dose cytarabine (CODOX-M/IVAC) for human immunodeficiency virus-associated Burkitt lymphoma. [Cancer. 2003]
Intensive chemotherapy with cyclophosphamide, doxorubicin, high-dose methotrexate/ifosfamide, etoposide, and high-dose cytarabine (CODOX-M/IVAC) for human immunodeficiency virus-associated Burkitt lymphoma.
Wang ES, Straus DJ, Teruya-Feldstein J, Qin J, Portlock C, Moskowitz C, Goy A, Hedrick E, Zelenetz AD, Noy A. Cancer. 2003 Sep 15; 98(6):1196-205.
Review Adult Burkitt lymphoma originating in the sphenoid sinus: case report and review of the literature. [Ear Nose Throat J. 2009]
Review Adult Burkitt lymphoma originating in the sphenoid sinus: case report and review of the literature.
Chennupati SK, Govindaraj S, Setzen G, Chiu AG. Ear Nose Throat J. 2009 Jul; 88(7):E07.
Review Sinonasal non-Hodgkin's lymphoma in patients infected with human immunodeficiency virus: report of three cases and review. [Clin Infect Dis. 1995]
Review Sinonasal non-Hodgkin's lymphoma in patients infected with human immunodeficiency virus: report of three cases and review.
Pomilla PV, Morris AB, Jaworek A. Clin Infect Dis. 1995 Jul; 21(1):137-49.

See reviews... See all...

Recent activity

Clear Turn Off Turn On

AIDS-related sinonasal Burkitt lymphoma successfully treated with intensive chem...
AIDS-related sinonasal Burkitt lymphoma successfully treated with intensive chemotherapy regimen and high active antiretroviral therapy.
Hematol Oncol Stem Cell Ther. 2011 ;4(1):41-4.

PubMed
Occupancy is nine-tenths of the law: occupancy rates determine the homogenizing ...
Occupancy is nine-tenths of the law: occupancy rates determine the homogenizing and differentiating effects of exotic species.
Am Nat. 2011 Apr ;177(4):535-43.

PubMed
Brain growth in Down syndrome subjects 15 to 22 weeks of gestational age and bir...
Brain growth in Down syndrome subjects 15 to 22 weeks of gestational age and birth to 60 months.
Clin Neuropathol. 1990 Jul-Aug ;9(4):181-90.

PubMed
Cost-effectiveness of universal screening of healthy newborns for nasal methicil...
Cost-effectiveness of universal screening of healthy newborns for nasal methicillin-resistant Staphylococcus aureus colonization at birth.
Infect Control Hosp Epidemiol. 2011 Mar ;32(3):301-2.

PubMed
900 MHz pulse-modulated radiofrequency radiation induces oxidative stress on hea...
900 MHz pulse-modulated radiofrequency radiation induces oxidative stress on heart, lung, testis and liver tissues.
Gen Physiol Biophys. 2011 Mar ;30(1):84-9.

PubMed

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

PubMed

Result Filters

Display Settings:

Send to:

AIDS-related sinonasal Burkitt lymphoma successfully treated with intensive chemotherapy regimen and high active antiretroviral therapy.

Source

Abstract

Publication Types, MeSH Terms

Publication Types

MeSH Terms

LinkOut - more resources

Other Literature Sources

Medical

Supplemental Content

Save items

Related citations in PubMed

Recent activity

Simple NCBI Directory

Getting Started

Resources

Popular

Featured

NCBI Information