Cleve Clin J Med. 2011 Apr;78(4):243-57.

Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others.

Kitzmiller JP, Groen DK, Phelps MA, Sadee W.

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Department of Pharmacology, Division of Clinical Trials, College of Medicine, The Ohio State University, Columbus, USA. joseph.kitzmiller@osumc.edu

Abstract

Genetics may account for much of the variability in our patients' responses to drug therapies. This article offers the clinician an up-to-date overview of pharmacogenomic testing, discussing implications and limitations of emerging validated tests relevant to the use of warfarin (Coumadin), clopidogrel (Plavix), statins, tamoxifen (Nolvadex), codeine, and psychotropic drugs. It also discusses the future role of pharmacogenomic testing in medicine.

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Pharmacogenomic testing: relevance in medical practice: why drugs work in some patients but not in others.

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