Immunology: Cross-dressers turn on T cells

Nature. 2011 Mar 31;471(7340):581-2. doi: 10.1038/471581a.

Abstract

Memory T cells remember viruses from previous infections, providing immunity by facilitating the killing of infected cells. For this, they exploit cross-dressing, the transfer of antigens between antigen-presenting cells.

Publication types

  • Comment
  • News

MeSH terms

  • Animals
  • Antigen Presentation / immunology*
  • Antigens, Viral / immunology
  • CD8-Positive T-Lymphocytes / cytology
  • CD8-Positive T-Lymphocytes / immunology*
  • Dendritic Cells / cytology
  • Dendritic Cells / immunology*
  • Dendritic Cells / metabolism
  • Histocompatibility Antigens Class I / immunology
  • Histocompatibility Antigens Class I / metabolism
  • Humans
  • Immunologic Memory / immunology*
  • Immunological Synapses
  • Lymphocyte Activation / immunology*
  • Mice
  • Models, Immunological*
  • Protein Transport
  • Virus Diseases / immunology
  • Virus Diseases / virology

Substances

  • Antigens, Viral
  • Histocompatibility Antigens Class I