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    Results: 5

    1.

    Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation.

    Zucchelli S, Marcuzzi F, Codrich M, Agostoni E, Vilotti S, Biagioli M, Pinto M, Carnemolla A, Santoro C, Gustincich S, Persichetti F.

    J Biol Chem. 2011 Jul 15;286(28):25108-17. Epub 2011 Mar 25.

    PMID:
    21454471
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    2.

    Huntingtin interacts with the cue domain of gp78 and inhibits gp78 binding to ubiquitin and p97/VCP.

    Yang H, Liu C, Zhong Y, Luo S, Monteiro MJ, Fang S.

    PLoS One. 2010 Jan 26;5(1):e8905.

    PMID:
    20126661
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    3.

    IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome.

    Thompson LM, Aiken CT, Kaltenbach LS, Agrawal N, Illes K, Khoshnan A, Martinez-Vincente M, Arrasate M, O'Rourke JG, Khashwji H, Lukacsovich T, Zhu YZ, Lau AL, Massey A, Hayden MR, Zeitlin SO, Finkbeiner S, Green KN, LaFerla FM, Bates G, Huang L, Patterson PH, Lo DC, Cuervo AM, Marsh JL, Steffan JS.

    J Cell Biol. 2009 Dec 28;187(7):1083-99. Epub 2009 Dec 21.

    PMID:
    20026656
    [PubMed - indexed for MEDLINE]
    Free PMC Article
    4.

    Ubiquitin ligase Hrd1 enhances the degradation and suppresses the toxicity of polyglutamine-expanded huntingtin.

    Yang H, Zhong X, Ballar P, Luo S, Shen Y, Rubinsztein DC, Monteiro MJ, Fang S.

    Exp Cell Res. 2007 Feb 1;313(3):538-50. Epub 2006 Nov 3.

    PMID:
    17141218
    [PubMed - indexed for MEDLINE]
    5.

    SUMO modification of Huntingtin and Huntington's disease pathology.

    Steffan JS, Agrawal N, Pallos J, Rockabrand E, Trotman LC, Slepko N, Illes K, Lukacsovich T, Zhu YZ, Cattaneo E, Pandolfi PP, Thompson LM, Marsh JL.

    Science. 2004 Apr 2;304(5667):100-4.

    PMID:
    15064418
    [PubMed - indexed for MEDLINE]

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